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Polymyxin-B·sulfate

research grade
(Aerosporin)
CAS [1405-20-5]

Ph. Eur. Mixture of the sulfates of polypeptides produced by the growth of certain strains of Bacillus polymyxa, the main component being Polymyxin B1.
Assay (HPLC): sum of Polymyxins B1, B2, B3 and B1-I min. 80 %; Polymyxin B3 max. 6 %; Polymyxin B1-I max. 15 % (all data based on dried substance).
Peptide antibiotic that mainly acts against Gram-negative bacteria. Causes changes in membrane structure resulting in leakage of small molecules.


References:
  1. Storm, D.R. et al. (1977) Ann. Rev. Biochem. 46, 723-63
WARNING
Hazard Statements H302
Precautions P264
Reaction P301 +P312 - P330
Storage P501

HS: 38210000
Storage Temperature: +2 °C to +8 °C


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Antibiotics in Mammalian Cell Culture: Table

Friday, May 25, 2012

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H302

Deutsch:

Gesundheitsschädlich bei Verschlucken.

English:

Harmful if swallowed.

Français:

Nocif en cas d'ingestion.

Italiano:

Nocivo se ingerito.

Español:

Nocivo en caso de ingestión.

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P264

Deutsch:

Nach Gebrauch … gründlich waschen.

English:

Wash … thoroughly after handling.

Français:

Se laver … soigneusement après manipulation.

Italiano:

Lavare accuratamente … dopo l’uso.

Español:

Lavarse … concienzudamente tras la manipulación.

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P301 +P312

Deutsch:

BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

Français:

EN CAS D’INGESTION: appeler un CENTRE ANTIPOISON ou un médecin en cas de malaise.

Italiano:

IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI o un medico.

Español:

EN CASO DE INGESTIÓN: Llamar a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico si se encuentra mal.

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P330

Deutsch:

Mund ausspülen.

English:

Rinse mouth.

Français:

Rincer la bouche.

Italiano:

Sciacquare la bocca.

Español:

Enjuagarse la boca.

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