Bacitracinresearch grade, USP
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Mr ca. 1422 • CAS [1405-87-4]
Bacitracin is a polypeptide antibiotic recovered from certain strains of B.
subtilis and B. licheniformis. It inhibits cell wall biosynthesis
in gram-positive bacteria and Neisseria by inhibition of peptidoglycan
synthesis. Bacitracin may as well be used as protease inhibitor.
Min. 60
000 IU/g. Main component Bacitracin A. Bactericidal activity requires divalent
cations like Zn2+ (1). The concentration of stock solution is 100 -
1000 mg/ml in H2O or ethanol, stored at -20 °C. The working
concentration is 0.1 - 1 mg/ml (0.07 - 0.7 mM). Bacitracin is very stable in a
pH range of 4 - 5, but is rapidly inactivated in pH of over 5 at room
temperature.
References:
- Scogin, D. et al. (1980) Biochemistry 19, 3348-52
EINECS: 215-786-2 • WGK: 2 • HS: 29419000
Storage Temperature: +2 °C to +8 °C