Aprotinin from bovine lunglyophil.
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Mr ca. 6500 • CAS [9087-70-1]
Purified inhibitor of trypsin, chymotrypsin, plasmin and especially kallikrein. For in vitro inhibition of fibrinolytic activity in blood samples (1). Activity: min. 3 Ph. Eur. Units (PEU)/mg, based on dried substance.
Unit definition: 1 Ph. Eur. Unit of aprotinin inhibits 50 % of the enzymatic activity of 2 microkatals trypsin, measured with BAEE as substrate at pH 8.0 and 25 °C.
Activity in other units: min. 5850 Kallikrein Inactivator Units (KIU)/mg, based on dried substance. (1 PEU = 1800 KIU).
Trasylol® = registered trademark of Bayer AG
References:
- Trautschold, E. et al. (1967) Biochem. Pharmacol. 16, 59-72
EINECS: 232-994-9 • WGK: 1 • HS: 35040090
Storage Temperature: +2 °C to +8 °C