Ion Exchangers

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SERVA Ion Exchange Media and Adsorber Resins

Ion exchangers are usually solid, macromolecular polyelectrolytes in the form of macroscopic particles with a porous structure. They are insoluble in water but capable of swelling. They are able to exchange bound ions against others dissolved in the surrounding medium. The cation exchangers (polyacids) carry fixed negatively charged functional groups (anchor groups grafted onto the polymer) with positive counter-ions, while the anion exchangers (polybases) have positively charged groups fixed onto the polymer with negative counter-ions to equalize the charge. Binding and release of the counter-ions are reversible processes and dependent on their concentration and affinity to the anchor groups.

There are inorganic ion exchangers which are natural aluminium silicates, e.g. Zeolites, which are used for water softening and desalting or Bentonite, which can be used for detoxification and as an adsorbent for proteins and viruses. Furthermore there are synthetic organic ion exchange resins, which are mainly produced by polymerization. They are of fundamental importance for many industrial applications and described below in more detail.

Ion exchangers on the basis of modified agarose, cellulose or dextran are used for the separation of large biomolecules, e.g. proteins or nucleic acids (see SERVACEL® Cellulose Ion Exchangers).

Adsorber resins have a similar basic matrix as ion exchange resins, but without functional groups. Binding of substances runs via non-ionic forces (see SERDOLIT®  PAD Resins).

Friday, November 21, 2014

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Markthalle:
November - Dezember 2014


Hier geht es zur Aktion

Große Herbstaktion -
10 Jahre SERVATIUS!


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Münster Conference on
Biomolecule Analysis


December 05, 2014

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The SERVA Catalog 2014
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New Application Note:
ICPL™ - Coupled Immunoprecipitation
(ICPL-IP)


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Verleihung des Transferpreises 2013/2014
der WWU Münster


an Prof. Dr. Simone König und SERVA Electrophoresis GmbH

 more

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Markthalle:
November - Dezember 2014

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Hier geht es zur Aktion

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Große Herbstaktion -
10 Jahre SERVATIUS!

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Hier geht es zur Aktion

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Münster Conference on
Biomolecule Analysis

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December 05, 2014

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Core Unit Proteomics
Interdisciplinary Centre for Clinical Research (IZKF)
Münster

 


Münster Conference Flyer (pdf)

New Brochures:
All you need for ...

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SERVA Brochure: 2D Electrophoresis (pdf)

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The SERVA Catalog 2014
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• Biochemicals A-Z

• Sample Preparation

• Electrophoresis

• Collagenase & Neutral Protease

• Life Sciences

• Enzymology

• Microscopy

• Ion Exchange Media

 


Find the SERVA Online Catalog 2014 here!

New Application Note:
ICPL™ - Coupled Immunoprecipitation
(ICPL-IP)

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ImmunoPrecipitation (IP) is widely used as a method to selectively isolate protein complexes from primary tissues. However, due to lack of specificity and selectivity of most antibodies and unspecific binding of the carrier beads, the method can produce false positives. The ICPL approach, employing stable isotope labelling and mass spectrometry, can discriminate true positive from false positive IP complexes.


SERVA ICPL™ Quadruplex Plus Kit 39233
Application Note: ICPL-IP

Verleihung des Transferpreises 2013/2014
der WWU Münster

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an Prof. Dr. Simone König und SERVA Electrophoresis GmbH

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Die Chemikerin Prof. Dr. Simone König erhielt am 3. Juni 2014 den
mit 20.000 € dotierten Transferpreis der Westfälischen Wilhelms-Univer-
sität (WWU) für die Verbesserung einer in der Labortechnik sehr häufig eingesetzten Methode der
Gel-Elektrophorese.

Geehrt wurde außerdem Günter Theßeling von der Firma SERVA Electrophoresis GmbH in Heidelberg, die die Entwicklung jetzt auf den Markt bringt.

Film: Von der Idee zum Mercator-Gel


Verleihung des WWU-Transferpreises 2013/2014.pdf

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