Ciprofloxacin Hydrochlorideresearch grade

CAS [86393-32-0]

Ciprofloxacin HCl is a second generation fluoroquinolone antibiotic.

Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication. Because DNA gyrase is required during DNA replication, subsequent DNA synthesis and cell division is inhibited.
Ciprofloxacin is a broad spectrum antibiotic targeting a wide variety of gram

positive and gram negative bacteria. Many mycoplasma strains, inclusive A. laidlawii, M. orale, M. hyorhinis, M. fermentas, and M. arginine, react sensitive to ciprofloxacin. Since these strains are responsible for most of the contaminations in cell culture, it can be used for removal of mycoplasma contamination. At the recommended concentration of ca. 1 µg/ml no cytotoxic effects occur.
Ciprofloxacin HCl is freely soluble at 35 mg/ml.



Content (dry substance)
pH
98.0 - 102.0 %
pH 3.5 – 4.5


References:
  1. Wolfson, John S., & Hooper D. C. (1985) Am. Soc. for Microbiol. 4th ser. 28, 581 - 86
WARNING
Hazard Statements H319 - H412
Precautions P264 - P273 - P280
Reaction P305 +P351 +P338 - P337 +P313

WGK: 2HS: 29419000
Storage Temperature: +2 °C to +8 °C

Cat.No.
Size
EUR
47977.01
5 g
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H319

Deutsch:

Verursacht schwere Augenreizung.

English:

Causes serious eye irritation.

Français:

Provoque une sévère irritation des yeux.

Italiano:

Provoca grave irritazione oculare.

Español:

Provoca irritación ocular grave.

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H412

Deutsch:

Schädlich für Wasserorganismen, mit langfristiger Wirkung.

English:

Harmful to aquatic life with long lasting effects.

Français:

Nocif pour les organismes aquatiques, entraîne des effets néfastes à long terme.

Italiano:

Nocivo per gli organismi acquatici con effetti di lunga durata.

Español:

Nocivo para los organismos acuáticos, con efectos nocivos duraderos.

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P264

Deutsch:

Nach Gebrauch … gründlich waschen.

English:

Wash … thoroughly after handling.

Français:

Se laver … soigneusement après manipulation.

Italiano:

Lavare accuratamente … dopo l’uso.

Español:

Lavarse … concienzudamente tras la manipulación.

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P273

Deutsch:

Freisetzung in die Umwelt vermeiden.

English:

Avoid release to the environment.

Français:

Éviter le rejet dans l’environnement.

Italiano:

Non disperdere nell’ambiente.

Español:

Evitar su liberación al medio ambiente.

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P280

Deutsch:

Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

English:

Wear protective gloves/protective clothing/eye protection/face protection.

Français:

Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.

Italiano:

Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.

Español:

Llevar guantes/prendas/gafas/máscara de protección.

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P305 +P351 +P338

Deutsch:

BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

English:

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Français:

EN CAS DE CONTACT AVEC LES YEUX: rincer avec précaution à l’eau pendant plusieurs minutes. Enlever les lentilles de contact si la victime en porte et si elles peuvent être facilement enlevées. Continuer à rincer

Italiano:

IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.

Español:

EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.

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P337 +P313

Deutsch:

Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

English:

If eye irritation persists: Get medical advice/attention.

Français:

Si l’irritation oculaire persiste: consulter un médecin.

Italiano:

Se l’irritazione degli occhi persiste, consultare un medico.

Español:

Si persiste la irritación ocular: Consultar a un médico.