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Propidium iodideresearch grade

(3,8-Diamino-5-(3-[diethylmethylammonio]propyl)-6-phenylphenan-thridinium·diiodide)
C27H34N42+·2I- • Mr 668.4 • CAS [25535-16-4]

For selective labelling of DNA in dead cells; used in tumor diagnosis (flow cytometry) (1, 2). Used as counter stain of nuclei in Annexin staining (detection of apoptotic cells). For the study of micronuclear morphology of protozoa (3).


References:
  1. Valet, G. et al. (1987) Blut 49, 37-43
  2. ibid. (1984) J. Clin. Chem. Clin. Biochem. 22, 935-42
  3. Fox, D.P. et al. (1987) Stain Technol. 62, 217-20
WARNING
Hazard Statements H315 - H319 - H335 - H341
Precautions P261 - P280
Reaction P302 +P352 - P304 +P340 - P305 +P351 +P338
Storage P405

Muta. 2 • EINECS: 247-081-0 • WGK: 2 • HS: 29239000
Storage Temperature: +2 °C to +8 °C

Cat.No.
Size
EUR
33671.01
25 mg
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H315

Deutsch:

Verursacht Hautreizungen.

English:

Causes skin irritation.

Français:

Provoque une irritation cutanée.

Italiano:

Provoca irritazione cutanea.

Español:

Provoca irritación cutánea.

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H319

Deutsch:

Verursacht schwere Augenreizung.

English:

Causes serious eye irritation.

Français:

Provoque une sévère irritation des yeux.

Italiano:

Provoca grave irritazione oculare.

Español:

Provoca irritación ocular grave.

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H335

Deutsch:

Kann die Atemwege reizen.

English:

May cause respiratory irritation.

Français:

Peut irriter les voies respiratoires.

Italiano:

Può irritare le vie respiratorie.

Español:

Puede irritar las vías respiratorias.

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H341

Deutsch:

Kann vermutlich genetische Defekte verursachen <Expositionsweg angeben, sofern schlüssig belegt ist, dass diese Gefahr bei keinem anderen Expositionsweg besteht>.

English:

Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Français:

Susceptible d'induire des anomalies génétiques <indiquer la voie d'exposition s'il est formellement prouvé qu'aucune autre voie d'exposition ne conduit au même danger>.

Italiano:

Sospettato di provocare alterazioni genetiche <indicare la via di esposizione se è accertato che nessun'altra via di esposizione comporta il medesimo pericolo>.

Español:

Se sospecha que provoca defectos genéticos <Indíquese la vía de exposición si se ha demostrado concluyentemente que el peligro no se produce por ninguna otra vía >.

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P261

Deutsch:

Einatmen von Staub/Rauch/Gas/Nebel/Dampf/A