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Phosphoramidonresearch grade

(N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-Leu-L-Trp·Na· 2H2O)
C23H32N3O10P·Na2 • Mr 587.5 • CAS [119942-99-3]

Inhibitor for thermolysin and neutral endopeptidase-24.11 (ANP Degradation Enzyme). Inhibits the activity of 'Endothelin Converting Enzyme' (3 - 9). Microbial product.
Store dry and protect from light!

Assay (HPLC)
min. 90.0 %


References:
  1. Suda, H. et al. (1973) J. Antibiotics 26, 621
  2. Roques, B.P. & Beaumont, A. (1990) Trends Pharmacol. Sci. 2, 245-9
  3. Gettins, P. (1988) J. Biol. Chem. 263, 10208-11
  4. Ikegawa, R. et al. (1990) Biochem. Biophys. Res. Commun. 171, 669-75
  5. Rae, G.A. et al. (1993) Eur. J. Pharmacol. 240, 113-9
  6. Patel, K.V. & Schrey, M.P. (1995) Br. J. Cancer 71, 442-7
  7. Fawzi, A.B. et al. (1994) Anal. Biochem. 222, 342-50
  8. Umekawa, T. et al. (1994) J. Pharmacol. Exp. Ther. 269, 860-6
  9. Ohnaka, K. et al. (1993) J. Biol. Chem. 268, 26759-66

HS: 29419000
Storage Temperature: +2 °C to +8 °C

Cat.No.
Size
EUR
32753.01
5 mg
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