Fos-Choline-13Anagrade

(N-Tridecylphosphocholine)
C18H40NO4P Mr 365,5 CAS [85775-42-4]

Lipids are commonly used by researchers to stabilize membrane proteins. However, the common challenge with working with lipids is their high cost and lack of solubility in water.

Anatrace® scientists answered the challenge and developed innovative Anatrace Fos-Choline® detergents.
The Fos-Choline detergents have been successfully used in membrane protein studies by NMR. Fos-Cholines employ charged amine and phosphate groups in combination with an alkyl chain to produce a zwitterionic surfactant. This unique architecture is water-soluble and capable of both stabilizing and keeping membrane proteins soluble in aqueous solutions. This surfactant also produces micelles and is able to extract membrane proteins from cellular membranes.



Purity (HPLC)
Solubility in H2O (0 - 5 °C)

≥ 99 %
≥ 20 %


References:
  1. Hwang, P. M. et al. (2002) Proc. Netl. Acad. Sci. USA 99, 13560-13565
  2. Oxenoid, K. & and Chou, J. J. (2005) Proc. Natl. Acad. Sci. USA 102, 10970-10875
  3. Evanics, F. et al. (2006) J. Am. Chem. Soc. 128, 8256-8264

HS: 29231000


Cat.No.
Size
EUR
60107.02
5 g
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60107.03
25 g
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