Phenylmethylsulfonyl fluorideresearch grade

(PMSF, Benzylsulfonyl fluorid, Toluenesulfonyl fluoride)
C7H7FO2SMr 174.19CAS [329-98-6]

Inhibits trypsin and chymotrypsin (1). Non-inhibitory to cholineesterase. Less toxic than diisopropylfluorophosphate (2). Inactivation of PMSF in buffer (3).

Assay (GC)
MP
min. 99.0 %
90 - 94 °C


References:
  1. Prouty, W.F. & Goldberg, A.L. (1972) J. Biol. Chem. 247, 3341-52
  2. Fahrney, D.E. & Gold, A.M. (1963) J. Am. Chem. Soc. 85, 997-1009
  3. James, G.T. (1978) Anal. Biochem. 86, 574-9
DANGER
Hazard Statements H301 - H314
Precautions P264 - P280
Reaction P301 +P310 - P301 +P330 +P331 - P303 +P361 +P353 - P305 +P351 +P338

GGVSE/ADR: 8 II UN2923IATA: 8 II UN2923EINECS: 206-350-2WGK: 1HS: 29049900
Storage Temperature: +15 °C to +30 °C

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H301

Deutsch:

Giftig bei Verschlucken.

English:

Toxic if swallowed.

Français:

Toxique en cas d'ingestion.

Italiano:

Tossico se ingerito.

Español:

Tóxico en caso de ingestión.

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H314

Deutsch:

Verursacht schwere Verätzungen der Haut und schwere Augenschäden.

English:

Causes severe skin burns and eye damage.

Français:

Provoque des brûlures de la peau et des lésions oculaires graves.

Italiano:

Provoca gravi ustioni cutanee e gravi lesioni oculari.

Español:

Provoca quemaduras graves en la piel y lesiones oculares graves.

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P264

Deutsch:

Nach Gebrauch … gründlich waschen.

English:

Wash … thoroughly after handling.

Français:

Se laver … soigneusement après manipulation.

Italiano:

Lavare accuratamente … dopo l’uso.

Español:

Lavarse … concienzudamente tras la manipulación.

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P280

Deutsch:

Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

English:

Wear protective gloves/protective clothing/eye protection/face protection.

Français:

Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.

Italiano:

Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.

Español:

Llevar guantes/prendas/gafas/máscara de protección.

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P301 +P310

Deutsch:

BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Français:

EN CAS D’INGESTION: appeler immédiatement un CENTRE ANTIPOISON ou un médecin.

Italiano:

IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI o un medico

Español:

EN CASO DE INGESTIÓN: Llamar inmediatamente a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico.

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P301 +P330 +P331

Deutsch:

BEI VERSCHLUCKEN: Mund ausspülen. KEIN Erbrechen herbeiführen.

English:

IF SWALLOWED: rinse mouth. Do NOT induce vomiting.

Français:

EN CAS D’INGESTION: rincer la bouche. NE PAS faire vomir.

Italiano:

IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.

Español:

EN CASO DE INGESTIÓN: Enjuagarse la boca. NO provocar el vómito.

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P303 +P361 +P353

Deutsch:

BEI KONTAKT MIT DER HAUT (oder dem Haar): Alle beschmutzten, getränkten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen/duschen.

English:

IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.

Français:

EN CAS DE CONTACT AVEC LA PEAU (ou les cheveux): enlever immédiatement les vêtements contaminés. Rincer la peau à l’eau/se doucher.

Italiano:

IN CASO DI CONTATTO CON LA PELLE (o con i capelli): togliersi di dosso immediatamente tutti gli indumenti contaminati. Sciacquare la pelle/fare una doccia.

Español:

EN CASO DE CONTACTO CON LA PIEL (o el pelo): Quitarse inmediatamente las prendas contaminadas. Aclararse la piel con agua o ducharse.

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P305 +P351 +P338

Deutsch:

BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

English:

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Français:

EN CAS DE CONTACT AVEC LES YEUX: rincer avec précaution à l’eau pendant plusieurs minutes. Enlever les lentilles de contact si la victime en porte et si elles peuvent être facilement enlevées. Continuer à rincer

Italiano:

IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.

Español:

EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.