Reagents A-Z
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Partner Catalogs
Hoefer Inc., USA

Equipment for Electrophoresis

Elchrom Scientific, CH

Equipment & Gels for DNA Electrophoresis

BioCision, USA

Standardizing Samples

Delphi™ Genetics SA

Cloning & Expression
in Bacteria

IMPLEN GmbH, D

NanoPhotometer
for Small Volumes

Isogen Life Science B.V.

Proxima Imaging Platform

Generon Ltd., UK

GST-tagged Protein Purification

Pro-Chem Inc., USA

Antibody Purification

 

HomeLife SciencesAntibiotics

Antibiotics

Antibiotics are low molecular weight secondary metabolites produced by certain strains of bacteria (mainly Bacillus species) and fungi (above all Streptomycetes). At low concentrations, they are either bactericidal by killing other microorganisms or bacteriostatic by reversibly inhibiting growth. The concept of antibiotics includes today also chemically or biochemically synthesized derivatives as well as substances from plants and animals with antibiotic activity. Antibiotics can be classified according to their mechanism of action.The major targets in the cell are:

  • Cell Wall Synthesis
  • Transcription and Replication
  • Protein Synthesis
  • Structure and Function of Cell Membranes
  • Besides, antibiotics can interact quite specifically in various metabolic pathways.
    In the research area, antibiotics are used in cell culture to prevent the growth of contaminating bacteria, fungi and mycoplasma. In Molecular Biology, some antibiotics can be used for the selection of resistant cell clones. Due to their specific mechanism of action, antibiotics are also valuable tools in the elucidation of cellular functions.
    In the following section, our antibiotics program is listed according to their mechanism of action.



    Wednesday, November 26, 2014

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    an Prof. Dr. Simone König und SERVA Electrophoresis GmbH

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    Markthalle:
    November - Dezember 2014

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    Münster Conference on
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    December 05, 2014

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    Core Unit Proteomics
    Interdisciplinary Centre for Clinical Research (IZKF)
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    • Biochemicals A-Z

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    New Application Note:
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    ImmunoPrecipitation (IP) is widely used as a method to selectively isolate protein complexes from primary tissues. However, due to lack of specificity and selectivity of most antibodies and unspecific binding of the carrier beads, the method can produce false positives. The ICPL approach, employing stable isotope labelling and mass spectrometry, can discriminate true positive from false positive IP complexes.


    SERVA ICPL™ Quadruplex Plus Kit 39233
    Application Note: ICPL-IP

    Verleihung des Transferpreises 2013/2014
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    an Prof. Dr. Simone König und SERVA Electrophoresis GmbH

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    Die Chemikerin Prof. Dr. Simone König erhielt am 3. Juni 2014 den
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    Geehrt wurde außerdem Günter Theßeling von der Firma SERVA Electrophoresis GmbH in Heidelberg, die die Entwicklung jetzt auf den Markt bringt.

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