Puromycin·2HClresearch grade

C22H29N7O5·2HClMr 544.4CAS [58-58-2]

From Streptomyces albo-niger. Free base (Mr 471.5) 86 %. Inhibitor of protein biosynthesis. Causes premature termination of the nascent polypeptide chain by its action as aminoacyl-tRNA analog (in procaryotes and eucaryotes).

Purity (HPLC, TLC)
min. 98.0 %


References:
  1. Vazquez, D. (1974) FEBS Lett. 40, 63-84
  2. Claeyssens, S. et al. (1993) FEBS Lett. 315, 7
WARNING
Hazard Statements H302
Precautions P264 - P270
Reaction P301 +P312 - P330

EINECS: 200-387-8WGK: 1HS: 29419000
Storage Temperature: -15 °C to -25 °C

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H302

Deutsch:

Gesundheitsschädlich bei Verschlucken.

English:

Harmful if swallowed.

Français:

Nocif en cas d'ingestion.

Italiano:

Nocivo se ingerito.

Español:

Nocivo en caso de ingestión.

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P264

Deutsch:

Nach Gebrauch … gründlich waschen.

English:

Wash … thoroughly after handling.

Français:

Se laver … soigneusement après manipulation.

Italiano:

Lavare accuratamente … dopo l’uso.

Español:

Lavarse … concienzudamente tras la manipulación.

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P270

Deutsch:

Bei Gebrauch nicht essen, trinken oder rauchen.

English:

Do no eat, drink or smoke when using this product.

Français:

Ne pas manger, boire ou fumer en manipulant ce produit.

Italiano:

Non mangiare, né bere, né fumare durante l’uso.

Español:

No comer, beber ni fumar durante su utilización.

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P301 +P312

Deutsch:

BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

Français:

EN CAS D’INGESTION: appeler un CENTRE ANTIPOISON ou un médecin en cas de malaise.

Italiano:

IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI o un medico.

Español:

EN CASO DE INGESTIÓN: Llamar a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico si se encuentra mal.

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P330

Deutsch:

Mund ausspülen.

English:

Rinse mouth.

Français:

Rincer la bouche.

Italiano:

Sciacquare la bocca.

Español:

Enjuagarse la boca.