Mycotoxin; antibiotic from Aspergillus and Penicillium species;
carcinogenic in rats (1). Effect on carbohydrate metabolism (2). Causes breaks
in DNA (3). Inhibits aminoacyl-tRNA synthetase (4). Influence on intracellular
ion flux and interaction with cellular membranes (5). Antitumor activity (6).
Assay (HPLC, TLC)
min. 98 %
References:
Dickens, F. et al. (1966) Brit. J. Cancer 20, 134
Sakthisekaran, D. et al. (1989) Biochem. Int. 19, 37-51
For his work on a new selective method to isolate and analyze phospho- and glycoproteins Fabio Polato from the University of Innsbruck received the SERVA Young Scientists Award 2010 during the "17. Arbeitstagung Mikromethoden in der Proteinchemie" (21 to 23 June 2010, Martinsried, Germany). Congratulations!
(in front: Fabio Polato (Universität Innsbruck) and Barbara Müller (SERVA, Heidelberg), background left: Helmut E. Meyer (Ruhr-Universität Bochum), right: Roland Kellner (MERCK, Darmstadt)
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R 23/24/25
Deutsch:
Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
English:
Toxic by inhalation, in contact with skin and if swallowed.
Français:
Toxique par inhalation, par contact avec la peau et par ingestion.
Italiano:
Tossico per inalazione, contatto con la pelle e per ingestione.
Español:
Tóxico por inhalación, por ingestión y en contacto con la piel.
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