Serine protease with very broad range of action: cleaves peptide bonds at the
carboxylic side of aliphatic, aromatic, and hydrophobic amino acids. Suitable
for the isolation of DNA and RNA (1, 3).
Unit definition: 1 unit is defined as the amount of enzyme that
liberates Folin-positive amino acids and peptides, corresponding to 1 µmol
tyrosine per minute at 37 °C and pH 7.4 using urea-denatured hemoglobin as
substrate (4)
Activities in other units: min. 8 DMC-U/mg. One DMC-Unit is that amount
of enzymatic activity which catalyzes the cleavage of 1 µmole equivalent
peptide bond from dimethylcasein per minute at 25 °C, pH 7.0, expressed in
terms of the appearance of new terminal amino groups.
Inhibitors for Proteinase: AEBSF (cat. no. 12745), (PEFABLOC®
SC (cat.no. 31682), PMSF (cat. no. 32395) and Diisopropylfluorophosphate (cat.
no. 77205). Extraneous activities: DNases and RNases not detectable.
References:
Ebeling, W. et al.(1974) Eur. J. Biochem. 47, 91-7
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H334
Deutsch:
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen.
English:
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Français:
Peut provoquer des symptômes allergiques ou d'asthme ou des difficultés respiratoires par inhalation.
Italiano:
Può provocare sintomi allergici o asmatici o difficoltà respiratorie se inalato.
Español:
Puede provocar síntomas de alergia o asma o dificultades respiratorias en caso de inhalación.
BEI EINATMEN: Bei Atembeschwerden an die frische Luft bringen und in einer Position
ruhigstellen, die das Atmen erleichtert.
English:
IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
Français:
EN CAS D’INHALATION: s'il y a difficulté à respirer, transporter la victime à l'extérieur et la maintenir au repos dans une position où elle peut confortablement respirer.
Italiano:
IN CASO DI INALAZIONE: se la respirazione è difficile, trasportare l'infortunato all’aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
Español:
EN CASO DE INHALACIÓN: Si respira con dificultad, transportar a la víctima al exterior y mantenerla en reposo en una posición confortable para respirar.
