Antifungal antibiotic that inhibits sterol and fatty acid biosynthesis.
Inhibits HMG-CoA synthetase activity. Induces apoptosis in tumor cell lines.
Packaged under argon. Protect from light!
Assay (TLC)
min. 98 %
References:
Omura, S. (1976) Bacteriol. Rev. 40, 681-697
Buttke, T.M. a. Ingram, L.O. (1978) Biochemistry 17, 5282-6
Omura, S. (1981) Meth. Enzymol. 72, 520-32
Pizer, E.S. et al. (1996) Cancer Res. 56, 2745-7
Fuuya, Y et al. (1997) Anticancer Res. 17, 4589-93
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