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Trichostatin A from Streptomyces platensis

C17H22N2O3 • Mr 302.4 • CAS [58880-19-6]

Antifungal antibiotic from Streptomyces platensis. Inhibits histone deacetylase and blocks cell cycle progression at the G1 phase in Hela cells. Induces apoptotic cell death in cancer cells.

Assay (HPLC, TLC)

 min. 97 %


References:
  1. Takahashi, I. et al. (1996) J. Antibiotics. 49, 453
  2. Taunton, J. et al. (1996) Science 272, 408-11
  3. Sowa, R. et al. (1997) Biochem. Biophys. Res. Commun. 241, 142
  4. Eickhoff, B. et al. (2000) J. Biol. Chem. 381, 1127-32

HS: 29419000
Storage Temperature: -15 °C to -25 °C


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36915.01 1 mg inquire*  
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Saturday, February 4, 2012

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