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Puromycin·2HCl

research grade
C22H29N7O5·2HClMr 544.4CAS [58-58-2]

From Streptomyces albo-niger. Free base (Mr 471.5) 86 %. Inhibitor of protein biosynthesis. Causes premature termination of the nascent polypeptide chain by its action as aminoacyl-t-RNA analog (in procaryotes and eucaryotes).

Purity (HPLC, TLC)
min. 98 %


References:
  1. Vazquez, D. (1974) FEBS Lett. 40, 63-84
  2. Claeyssens, S. et al. (1993) FEBS Lett. 315, 7
WARNING
Hazard Statements H302 - H341
Precautions P201 - P281
Reaction P301 +P312 - P308 +P313 - P330

EINECS: 200-387-8WGK: 1HS: 29419000
Storage Temperature: -15 °C to -25 °C


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33835.01 10 mg inquire*  
33835.02 50 mg inquire*  
33835.03 250 mg inquire*  
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Thursday, May 24, 2012

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H302

Deutsch:

Gesundheitsschädlich bei Verschlucken.

English:

Harmful if swallowed.

Français:

Nocif en cas d'ingestion.

Italiano:

Nocivo se ingerito.

Español:

Nocivo en caso de ingestión.

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H341

Deutsch:

Kann vermutlich genetische Defekte verursachen <Expositionsweg angeben, sofern schlüssig belegt ist, dass diese Gefahr bei keinem anderen Expositionsweg besteht>.

English:

Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Français:

Susceptible d'induire des anomalies génétiques <indiquer la voie d'exposition s'il est formellement prouvé qu'aucune autre voie d'exposition ne conduit au même danger>.

Italiano:

Sospettato di provocare alterazioni genetiche <indicare la via di esposizione se è accertato che nessun'altra via di esposizione comporta il medesimo pericolo>.

Español:

Se sospecha que provoca defectos genéticos <Indíquese la vía de exposición si se ha demostrado concluyentemente que el peligro no se produce por ninguna otra vía >.

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P201

Deutsch:

Vor Gebrauch besondere Anweisungen einholen.

English:

Obtain special instructions before use.

Français:

Se procurer les instructions avant utilisation.

Italiano:

Procurarsi istruzioni specifiche prima dell’uso.

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Pedir instrucciones especiales antes del uso.

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P281

Deutsch:

Vorgeschriebene persönliche Schutzausrüstung verwenden.

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Use personal protective equipment as required.

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Utiliser l’équipement de protection individuel requis.

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Utilizzare il dispositivo di protezione individuale richiesto.

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Utilizar el equipo de protección individual obligatorio.

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P301 +P312

Deutsch:

BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

Français:

EN CAS D’INGESTION: appeler un CENTRE ANTIPOISON ou un médecin en cas de malaise.

Italiano:

IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI o un medico.

Español:

EN CASO DE INGESTIÓN: Llamar a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico si se encuentra mal.

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P308 +P313

Deutsch:

BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

English:

IF exposed or concerned: Get medical advice/attention.

Français:

EN CAS d’exposition prouvée ou suspectée: consulter un médecin.

Italiano:

IN CASO di esposizione o di possibile esposizione, consultare un medico.

Español:

EN CASO DE exposición manifiesta o presunta: Consultar a un médico.

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P330

Deutsch:

Mund ausspülen.

English:

Rinse mouth.

Français:

Rincer la bouche.

Italiano:

Sciacquare la bocca.

Español:

Enjuagarse la boca.

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