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Phorbol (12-myristoyl-13-acetyl)

analytical grade
(PMA, TPA, 12-O-Tetradecanoylphorbol-13-acetate)
C36H56O8Mr 616.8CAS [16561-29-8]

Antileukemic agent (1). Activates proteinkinase C (2). Strong inducer of tumor formation, favorite derivative for in vitro studies, interferon inducer, along with phytohemagglutinin (3).

Purity (TLC)
min. 99 %


References:
  1. Weinberg, J.B. (1981) Science 213, 665-7
  2. Skoglund, G. et al. (1985) Eur. J. Biochem. 148, 407-12
  3. Yip, Y.K. et al. (1981) Proc. Natl. Acad. Sci. USA 78, 1601-5
DANGER
Hazard Statements H300 - H310 - H330
Precautions P260 - P280
Reaction P301 +P310 - P302 +P350 - P304 +P340 - P310

MAK/TRK: 10 ml/m3, 50 mg/m3 for chloroformGGVSE/ADR: 6.1 II UN2811IATA: 6.1 II UN2811WGK: 3HS: 29159000
Storage Temperature: -15 °C to -25 °C


Cat.No. Size EUR
32496.01 1 mg inquire*  
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Thursday, May 24, 2012

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H300

Deutsch:

Lebensgefahr bei Verschlucken.

English:

Fatal if swallowed.

Français:

Mortel en cas d'ingestion.

Italiano:

Letale se ingerito.

Español:

Mortal en caso de ingestión.

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H310

Deutsch:

Lebensgefahr bei Hautkontakt.

English:

Fatal in contact with skin.

Français:

Mortel par contact cutané.

Italiano:

Letale per contatto con la pelle.

Español:

Mortal en contacto con la piel.

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H330

Deutsch:

Lebensgefahr bei Einatmen.

English:

Fatal if inhaled.

Français:

Mortel par inhalation.

Italiano:

Letale se inalato.

Español:

Mortal en caso de inhalación.

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P260

Deutsch:

Staub/Rauch/Gas/Nebel/Dampf/Aerosol nicht einatmen.

English:

Do not breathe dust/fume/gas/mist/vapours/spray.

Français:

Ne pas respirer les poussières/fumées/gaz/brouillards/vapeurs/aérosols.

Italiano:

Non respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.

Español:

No respirar el polvo/el humo/el gas/la niebla/los vapores/el aerosol.

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P280

Deutsch:

Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

English:

Wear protective gloves/protective clothing/eye protection/face protection.

Français:

Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.

Italiano:

Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.

Español:

Llevar guantes/prendas/gafas/máscara de protección.

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P301 +P310

Deutsch:

BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Français:

EN CAS D’INGESTION: appeler immédiatement un CENTRE ANTIPOISON ou un médecin.

Italiano:

IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI o un medico

Español:

EN CASO DE INGESTIÓN: Llamar inmediatamente a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico.

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P302 +P350

Deutsch:

BEI KONTAKT MIT DER HAUT: Behutsam mit viel Wasser und Seife waschen.

English:

IF ON SKIN: Gently wash with plenty of soap and water.

Français:

EN CAS DE CONTACT AVEC LA PEAU: laver avec précaution et abondamment à l’eau et au savon.

Italiano:

IN CASO DI CONTATTO CON LA PELLE: lavare delicatamente e abbondantemente con acqua e sapone.

Español:

EN CASO DE CONTACTO CON LA PIEL: Lavar suavemente con agua y jabón abundantes.

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P304 +P340

Deutsch:

BEI EINATMEN: An die frische Luft bringen und in einer Position ruhigstellen, die das Atmen erleichtert.

English:

IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Français:

EN CAS D’INHALATION: transporter la victime à l’extérieur et la maintenir au repos dans une position où elle peut confortablement respirer.

Italiano:

IN CASO DI INALAZIONE: trasportare l'infortunato all’aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.

Español:

EN CASO DE INHALACIÓN: Transportar a la víctima al exterior y mantenerla en reposo en una posición confortable para respirar.

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P310

Deutsch:

Sofort GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

Immediately call a POISON CENTER or doctor/physician.

Français:

Appeler immédiatement un CENTRE ANTIPOISON ou un médecin.

Italiano:

Contattare immediatamente un CENTRO ANTIVELENI o un medico.

Español:

Llamar inmediatamente a un CENTRO DE INFORMACION TOXICOLOGICA o a un médico.

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