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Dexamethasone

research grade
(Fluoro-11β,17,21-trihydroxy-16α-methyl-1,4-pregnadiene 3,20dione, Prednisolone F, Pregnadiene-3,20-dione-9α-fluoro-16αmethyl-11β,17α,21-triol, Fluoro-16α-methylprednisolone(3,20-dione))
C22H29FO5Mr 392.5CAS [50-02-2]

Selectively regulates the activity of enzymatic markers of cerebral endothelial cell lines (1). Inhibits the expression of the inducible but not the constitutive nitric oxide synthase in vascular endothelial cells.

Assay (UV)
97.0 - 103.0 %


References:
  1. Juillerat-Jeanneret, L. et al. (1992) In Vitro Cell Cev. Biol. 28A,537-43
  2. Radomski, M.W. et al. (1990) Proc. Natl. Acad. Sci. USA 87, 10043
DANGER
Hazard Statements H315 - H319 - H335 - H360Df
Precautions P281 - P285
Reaction P302 +P352 - P304 +P340 - P305 +P351 +P338 - P342 +P311

EINECS: 200-003-9WGK: 1HS: 29372100
Storage Temperature: +15 °C to +30 °C


Cat.No. Size EUR
18660.01 100 mg inquire*  
18660.02 1 g inquire*  
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Specifications
Sicherheitsdatenblatt
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H315

Deutsch:

Verursacht Hautreizungen.

English:

Causes skin irritation.

Français:

Provoque une irritation cutanée.

Italiano:

Provoca irritazione cutanea.

Español:

Provoca irritación cutánea.

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H319

Deutsch:

Verursacht schwere Augenreizung.

English:

Causes serious eye irritation.

Français:

Provoque une sévère irritation des yeux.

Italiano:

Provoca grave irritazione oculare.

Español:

Provoca irritación ocular grave.

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H335

Deutsch:

Kann die Atemwege reizen.

English:

May cause respiratory irritation.

Français:

Peut irriter les voies respiratoires.

Italiano:

Può irritare le vie respiratorie.

Español:

Puede irritar las vías respiratorias.

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H360Df

Deutsch:

Kann das Kind im Mutterleib schädigen. Kann vermutlich die Fruchtbarkeit beeinträchtigen.

English:

May damage the unborn child. Suspected of damaging fertility.

Français:

Peut nuire au foetus. Susceptible de nuire à la fertilité.

Italiano:

Può nuocere al feto. Sospettato di nuocere alla fertilità.

Español:

Puede dañar al feto. Se sospecha que perjudica a la fertilidad.

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P281

Deutsch:

Vorgeschriebene persönliche Schutzausrüstung verwenden.

English:

Use personal protective equipment as required.

Français:

Utiliser l’équipement de protection individuel requis.

Italiano:

Utilizzare il dispositivo di protezione individuale richiesto.

Español:

Utilizar el equipo de protección individual obligatorio.

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P285

Deutsch:

Bei unzureichender Belüftung Atemschutz tragen.

English:

In case of inadequate ventilation wear respiratory protection.

Français:

Lorsque la ventilation du local est insuffisante, porter un équipement de protection respiratoire.

Italiano:

In caso di ventilazione insufficiente utilizzare un apparecchio respiratorio.

Español:

En caso de ventilación insuficiente, llevar equipo de protección respiratoria.

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P302 +P352

Deutsch:

BEI KONTAKT MIT DER HAUT: Mit viel Wasser und Seife waschen.

English:

IF ON SKIN: Wash with plenty of soap and water.

Français:

EN CAS DE CONTACT AVEC LA PEAU: laver abondamment à l’eau et au savon.

Italiano:

IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua e sapone.

Español:

EN CASO DE CONTACTO CON LA PIEL: Lavar con agua y jabón abundantes.

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P304 +P340

Deutsch:

BEI EINATMEN: An die frische Luft bringen und in einer Position ruhigstellen, die das Atmen erleichtert.

English:

IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Français:

EN CAS D’INHALATION: transporter la victime à l’extérieur et la maintenir au repos dans une position où elle peut confortablement respirer.

Italiano:

IN CASO DI INALAZIONE: trasportare l'infortunato all’aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.

Español:

EN CASO DE INHALACIÓN: Transportar a la víctima al exterior y mantenerla en reposo en una posición confortable para respirar.

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P305 +P351 +P338

Deutsch:

BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

English:

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Français:

EN CAS DE CONTACT AVEC LES YEUX: rincer avec précaution à l’eau pendant plusieurs minutes. Enlever les lentilles de contact si la victime en porte et si elles peuvent être facilement enlevées. Continuer à rincer

Italiano:

IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.

Español:

EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.

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P342 +P311

Deutsch:

Bei Symptomen der Atemwege: GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.

Français:

En cas de symptômes respiratoires: appeler un CENTRE ANTIPOISON ou un médecin.

Italiano:

In caso di sintomi respiratori: contattare un CENTRO ANTIVELENI o un medico.

Español:

En caso de síntomas respiratorios: Llamar a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico.

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