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Cycloheximide

cryst. pure
(Actidione®, ββ Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-glutarimide))
C15H23NO4Mr 281.4CAS [66-81-9]

Antibiotic against yeasts at a concentration of 0.1 mg/ml (1). Inhibitor of protein biosynthesis (2).
Acid stable.

Assay (TLC)
Assay (HPLC)
MP
min. 95.0 %
min. 90.0 %
98 - 112 °C
Actidione = registered trademark of Upjohn.


References:
  1. Lee, B.K. & Wilkie, D. (1965) Nature 206, 90-2
  2. Jackson, L.G. & Studzinski, G.T. (1968) Exp. Cell Res. 52, 408-18
DANGER
Hazard Statements H300 - H341 - H360D - H411
Precautions P201 - P264 - P273 - P281
Reaction P301 +P310

Mut.Cat.: 3, Rep.Cat: 2EG-Index: 613-140-00-8GGVSE/ADR: 6.1 I UN2811IATA: 6.1 I UN2811EINECS: 200-636-0WGK: 3LHS: 29419000
Storage Temperature: +2 °C to +8 °C


Cat.No. Size EUR
10700.04 1 g inquire*  
10700.02 5 g inquire*  
10700.03 25 g inquire*  
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H300

Deutsch:

Lebensgefahr bei Verschlucken.

English:

Fatal if swallowed.

Français:

Mortel en cas d'ingestion.

Italiano:

Letale se ingerito.

Español:

Mortal en caso de ingestión.

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H341

Deutsch:

Kann vermutlich genetische Defekte verursachen <Expositionsweg angeben, sofern schlüssig belegt ist, dass diese Gefahr bei keinem anderen Expositionsweg besteht>.

English:

Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Français:

Susceptible d'induire des anomalies génétiques <indiquer la voie d'exposition s'il est formellement prouvé qu'aucune autre voie d'exposition ne conduit au même danger>.

Italiano:

Sospettato di provocare alterazioni genetiche <indicare la via di esposizione se è accertato che nessun'altra via di esposizione comporta il medesimo pericolo>.

Español:

Se sospecha que provoca defectos genéticos <Indíquese la vía de exposición si se ha demostrado concluyentemente que el peligro no se produce por ninguna otra vía >.

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H360D

Deutsch:

Kann das Kind im Mutterleib schädigen.

English:

May damage the unborn child.

Français:

Peut nuire au foetus.

Italiano:

Può nuocere al feto.

Español:

Puede dañar al feto.

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H411

Deutsch:

Giftig für Wasserorganismen, mit langfristiger Wirkung.

English:

Toxic to aquatic life with long lasting effects.

Français:

Toxique pour les organismes aquatiques, entraîne des effets néfastes à long terme.

Italiano:

Tossico per gli organismi acquatici con effetti di lunga durata.

Español:

Tóxico para los organismos acuáticos, con efectos nocivos duraderos.

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P201

Deutsch:

Vor Gebrauch besondere Anweisungen einholen.

English:

Obtain special instructions before use.

Français:

Se procurer les instructions avant utilisation.

Italiano:

Procurarsi istruzioni specifiche prima dell’uso.

Español:

Pedir instrucciones especiales antes del uso.

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P264

Deutsch:

Nach Gebrauch … gründlich waschen.

English:

Wash … thoroughly after handling.

Français:

Se laver … soigneusement après manipulation.

Italiano:

Lavare accuratamente … dopo l’uso.

Español:

Lavarse … concienzudamente tras la manipulación.

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P273

Deutsch:

Freisetzung in die Umwelt vermeiden.

English:

Avoid release to the environment.

Français:

Éviter le rejet dans l’environnement.

Italiano:

Non disperdere nell’ambiente.

Español:

Evitar su liberación al medio ambiente.

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P281

Deutsch:

Vorgeschriebene persönliche Schutzausrüstung verwenden.

English:

Use personal protective equipment as required.

Français:

Utiliser l’équipement de protection individuel requis.

Italiano:

Utilizzare il dispositivo di protezione individuale richiesto.

Español:

Utilizar el equipo de protección individual obligatorio.

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P301 +P310

Deutsch:

BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Français:

EN CAS D’INGESTION: appeler immédiatement un CENTRE ANTIPOISON ou un médecin.

Italiano:

IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI o un medico

Español:

EN CASO DE INGESTIÓN: Llamar inmediatamente a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico.

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