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Colistin sulfate

(Polymyxin E sulfate)
C₅₃H₁₀₄N₁₆O₂₁S₂ • M_r 1365.6 • CAS [1264-72-8]

Ph. Eur. Peptide antibiotic. Mixture of the sulfates of polypeptides produced by certain strains of Bacillus polymyxa var. colistinus. Acts mainly against Gram-negative bacteria. Causes changes in membrane structure resulting in leakage of small molecules. Soluble in water; stable between pH 2 - 6 at 4 °C. Protect from light.

Assay (HPLC)
(sum of polymyxins E1, E2, E3,
E1 - I and E1 -7 MOA)

min. 77.0 %

References:

Storm, D.R. et al. (1977) Ann. Rev. Biochem. 46, 723-63

DANGER

Hazard Statements	H301
Reaction	P301 +P310 - P321 - P330
Storage	P405 - P501

GGVSE/ADR: 6.1 III UN2811 • IATA: 6.1 III UN2811 • EINECS: 215-034-3 • WGK: 1 • HS: 29419000
Storage Temperature: +2 °C to +8 °C

Cat.No.	Size	EUR
17420.01	250 mg	inquire*
17420.02	1 g	inquire*
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Specifications

Sicherheitsdatenblatt

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Saturday, February 11, 2012

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H301

Deutsch:

Giftig bei Verschlucken.

English:

Toxic if swallowed.

Français:

Toxique en cas d'ingestion.

Italiano:

Tossico se ingerito.

Español:

Tóxico en caso de ingestión.

P301 +P310

Deutsch:

BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Français:

EN CAS D’INGESTION: appeler immédiatement un CENTRE ANTIPOISON ou un médecin.

Italiano:

IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI o un medico

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P321

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Besondere Behandlung (siehe … auf diesem Kennzeichnungsetikett).

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Specific treatment (see … on this label).

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P330

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P405

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Store locked up.

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