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Cerulenin from Cephalosporium caerulens
research grade
C12H17NO3 • Mr 223.27 • CAS [17397-89-6]
Antifungal antibiotic that inhibits sterol and fatty acid biosynthesis. Inhibits HMG-CoA synthetase activity. Induces apoptosis in tumor cell lines. Packaged under argon.
Protect from light!
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Assay (TLC) |
min. 98 % |
References:
- Omura, S. (1976) Bacteriol. Rev. 40, 681-697
- Buttke, T.M. a. Ingram, L.O. (1978) Biochemistry 17, 5282-6
- Omura, S. (1981) Meth. Enzymol. 72, 520-32
- Pizer, E.S. et al. (1996) Cancer Res. 56, 2745-7
- Fuuya, Y et al. (1997) Anticancer Res. 17, 4589-93
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| WARNING |
| Hazard Statements | H302 - H312 - H332 |
| Precautions | P264 - P270 |
| Reaction | P301 +P312 - P330 |
| Storage | P501 |
EINECS: 241-424-8 • HS: 29419000
Storage Temperature: +2 °C to +8 °C
| Cat.No. | Size | EUR |  |
|---|---|---|---|
| 16487.01 | 1 mg | inquire* | |
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