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Brefeldin A

research grade
C16H24O4 • Mr 280.4 • CAS [20350-15-6]

Macrolide antibiotic from Penicillium brefeldianum. Specifically inhibits translocation of proteins from the endoplasmic reticulum to the Golgi apparatus.

Assay (TLC)
min. 98 %


References:
  1. Capparelli, A.W. et al. (1993) Am. J. Physiol. 264, C40-7
  2. Cluett, E.B. et al. (1993) J. Cell Biol. 120, 15-24
  3. Driouich, A. et al. (1993) Plant Physiol. 101, 1363-73
  4. Uhlin-Hansen, L. & Yanagishita, M. (1993) Biol. Chem. 268, 17370-6
  5. Calabro, A. & Hascall, V. (1994) J. Biol. Chem. 269, 22771-8
  6. Turi, T.G. et al. (1994) J. Biol. Chem. 269, 24229-36
WARNING
Hazard Statements H302 - H312 - H332
Precautions P261 - P280
Reaction P301 +P312 - P302 +P352 - P304 +P340 - P330

WGK: 1 • HS: 29419000
Storage Temperature: -15 °C to -25 °C


Cat.No. Size EUR
15100.01 1 mg inquire*  
15100.02 5 mg inquire*  
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H302

Deutsch:

Gesundheitsschädlich bei Verschlucken.

English:

Harmful if swallowed.

Français:

Nocif en cas d'ingestion.

Italiano:

Nocivo se ingerito.

Español:

Nocivo en caso de ingestión.

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H312

Deutsch:

Gesundheitsschädlich bei Hautkontakt.

English:

Harmful in contact with skin.

Français:

Nocif par contact cutané.

Italiano:

Nocivo per contatto con la pelle.

Español:

Nocivo en contacto con la piel.

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H332

Deutsch:

Gesundheitsschädlich bei Einatmen.

English:

Harmful if inhaled.

Français:

Nocif par inhalation.

Italiano:

Nocivo se inalato.

Español:

Nocivo en caso de inhalación.

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P261

Deutsch:

Einatmen von Staub/Rauch/Gas/Nebel/Dampf/Aerosol vermeiden.

English:

Avoid breathing dust/fume/gas/mist/vapours/spray.

Français:

Éviter de respirer les poussières/fumées/gaz/brouillards/vapeurs/aérosols.

Italiano:

Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.

Español:

Evitar respirar el polvo/el humo/el gas/la niebla/los vapores/el aerosol.

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P280

Deutsch:

Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

English:

Wear protective gloves/protective clothing/eye protection/face protection.

Français:

Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.

Italiano:

Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.

Español:

Llevar guantes/prendas/gafas/máscara de protección.

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P301 +P312

Deutsch:

BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

Français:

EN CAS D’INGESTION: appeler un CENTRE ANTIPOISON ou un médecin en cas de malaise.

Italiano:

IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI o un medico.

Español:

EN CASO DE INGESTIÓN: Llamar a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico si se encuentra mal.

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P302 +P352

Deutsch:

BEI KONTAKT MIT DER HAUT: Mit viel Wasser und Seife waschen.

English:

IF ON SKIN: Wash with plenty of soap and water.

Français:

EN CAS DE CONTACT AVEC LA PEAU: laver abondamment à l’eau et au savon.

Italiano:

IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua e sapone.

Español:

EN CASO DE CONTACTO CON LA PIEL: Lavar con agua y jabón abundantes.

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P304 +P340

Deutsch:

BEI EINATMEN: An die frische Luft bringen und in einer Position ruhigstellen, die das Atmen erleichtert.

English:

IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Français:

EN CAS D’INHALATION: transporter la victime à l’extérieur et la maintenir au repos dans une position où elle peut confortablement respirer.

Italiano:

IN CASO DI INALAZIONE: trasportare l'infortunato all’aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.

Español:

EN CASO DE INHALACIÓN: Transportar a la víctima al exterior y mantenerla en reposo en una posición confortable para respirar.

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P330

Deutsch:

Mund ausspülen.

English:

Rinse mouth.

Français:

Rincer la bouche.

Italiano:

Sciacquare la bocca.

Español:

Enjuagarse la boca.

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