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Aprotinin from bovine lung

lyophil.
(Trypsin inhibitor from bovine lung, Trasylol®)
Mr ca. 6500CAS [9087-70-1]

Purified inhibitor of trypsin, chymotrypsin, plasmin and especially kallikrein. For in vitro inhibition of fibrinolytic activity in blood samples (1).

Unit definition: 1 IU (inhibitor unit) inhibits 1 U trypsin as defined by cleavage of 1 µmol BAEE (N-benzoyl-L-arginine ethyl ester) per minute (see under trypsin, cat.no. 37291).
Activity in other units: min. 3 Ph. Eur. Units (PEU)/mg, based on dried substance. Unit definition: 1 Ph. Eur. Unit of aprotinin inhibits 50 % of the enzymatic activity of 2 microkatals trypsin, measured with BAEE as substrate at pH 8.0 and 25 °C.
Activity in other units: min. 5850 Kallikrein Inactivator Units (KIU)/mg, based on dried substance. (KIU = PEU x 60 x 32,5).
Trasylol® = registered trademark of Bayer AG


References:
  1. Trautschold, E. et al. (1967) Biochem. Pharmacol. 16, 59-72
WARNING
Hazard Statements H302
Precautions P264 - P270
Reaction P301 +P312 - P330

EINECS: 232-994-9WGK: 1HS: 35040090
Storage Temperature: +2 °C to +8 °C


Cat.No. Size EUR
13718.01 10 mg inquire*  
13718.02 25 mg inquire*  
13718.03 100 mg inquire*  
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Specifications
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Additional Information 
Protease Inhibitors: Application Table


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Tuesday, May 22, 2012

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H302

Deutsch:

Gesundheitsschädlich bei Verschlucken.

English:

Harmful if swallowed.

Français:

Nocif en cas d'ingestion.

Italiano:

Nocivo se ingerito.

Español:

Nocivo en caso de ingestión.

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P264

Deutsch:

Nach Gebrauch … gründlich waschen.

English:

Wash … thoroughly after handling.

Français:

Se laver … soigneusement après manipulation.

Italiano:

Lavare accuratamente … dopo l’uso.

Español:

Lavarse … concienzudamente tras la manipulación.

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P270

Deutsch:

Bei Gebrauch nicht essen, trinken oder rauchen.

English:

Do no eat, drink or smoke when using this product.

Français:

Ne pas manger, boire ou fumer en manipulant ce produit.

Italiano:

Non mangiare, né bere, né fumare durante l’uso.

Español:

No comer, beber ni fumar durante su utilización.

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P301 +P312

Deutsch:

BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

Français:

EN CAS D’INGESTION: appeler un CENTRE ANTIPOISON ou un médecin en cas de malaise.

Italiano:

IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI o un medico.

Español:

EN CASO DE INGESTIÓN: Llamar a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico si se encuentra mal.

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P330

Deutsch:

Mund ausspülen.

English:

Rinse mouth.

Français:

Rincer la bouche.

Italiano:

Sciacquare la bocca.

Español:

Enjuagarse la boca.

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