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Aphidicolin

research grade
C20H34O4 • Mr 338.5 • CAS [38966-21-1]

Antibiotic isolated from Nigrospora oryzae (1). Tetracyclic diterpene with antiviral and antimitotic properties. Blocks the cell cycle at early S-phase. Specific inhibitor of α-type polymerase (eucaryotic and viral coded) (2).

Assay (TLC)
min. 97 %


References:
  1. Hubermann, J.A. (1981) Cell 23, 647-8
  2. Spadari, S. et al. (1982) Trends Biochem. Sci. 7, 29-32
 XN 
Harmful
R: 20/22 - 68
S: 28B - 36/37

WGK: 1 • HS: 29419000
Storage Temperature: +2 °C to +8 °C


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13696.02 1 mg inquire*  
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Specifications
Sicherheitsdatenblatt
Material Safety Data Sheet

Friday, July 30, 2010

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R 20/22

Deutsch:

Gesundheitsschädlich beim Einatmen und Verschlucken.

English:

Harmful by inhalation and if swallowed.

Français:

Nocif par inhalation et par ingestion.

Italiano:

Nocivo per inalazione e ingestione.

Español:

Nocivo por inhalación y por ingestión.

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R 68

Deutsch:

Irreversibler Schaden möglich.

English:

Possible risk of irreversible effects.

Français:

Possibilité d'effets irréversibles.

Italiano:

Possibilità di effetti irreversibili.

Español:

Posibilidad de efectos irreversibles.

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S 36/37

Deutsch:

Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

English:

Wear suitable protective clothing and gloves.

Français:

Porter un vètement de protection et des gants appropriés.

Italiano:

Usare indumenti protettivi e guanti adatti.

Español:

Úsense indumentaria y guantes de protección adecuados.

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