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Wortmannin from Penicillium fumiculosum

research grade
C23H24O8 • Mr 428.4 • CAS [19545-26-7]

Potent selective inhibitor of phosphatidylinositol-3-kinase (PI 3 kinase) and DNA dependent protein kinase, which is known to mediate DNA double strand break repair. Induces apoptosis and also sensitizes cells to ionizing radiation.

Assay (TLC/HPLC)
Solubility

 min. 97.5 %
5 mg/ml in methanol
Packaged under argon. Protect from light!


References:
  1. Boulton, S. et al. (1996) Carcinogenesis 17, 2285-90
  2. Ng, S.S.W. et al. ((2000) Cancer Res. 60, 5451-5
  3. Kubota, N. et al. (2000) Cancer Lett. 161, 141-7

HS: 29419000
Storage Temperature: +2 °C to +8 °C


Cat.No. Size EUR
38385.01 1 mg inquire*  
38385.02 5 mg inquire*  
38385.03 10 mg inquire*  
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Monday, May 21, 2012

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